Virus activation by vitamin A and NO2 gas exposures in hamsters.
نویسنده
چکیده
Hamsters exposed to 10 ppm NO2 for 5 hr once a week for 4 weeks while undergoing acute vitamin A deficiency showed much reduced epithelial cell regeneration in the terminal bronchioles. Quantitative analysis done by autoradiography and scintillation counting from lung tissues indicates much reduced cell kinetics occurring in terminal bronchiolar alveolar region. Alveolar necrosis was often observed and no type II cell reversion occurred. Virus particles were found within the alveolar epithelial plasma membrane.
منابع مشابه
Distribution and determinants of personal exposure to nitrogen dioxide in school children.
OBJECTIVES To assess the distribution of personal exposures to nitrogen dioxide (NO2) in school children, and to investigate factors that might influence personal exposure. METHODS NO2 exposures were assessed by use of passive diffusion tubes for 46 children aged 9-11 years, selected from two Southampton schools. The tubes were worn for seven days, and parallel measurements were made with sta...
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Nitrogen dioxide (NO2), a combustion-generated oxidant gas, is widely present in indoor and outdoor environments. Outdoors, where it comes primarily from combustion engines, industry, and power generation, it is a precursor to particles and ozone. Indoors, NO2 is generated by gas cooking and heating, and it exists as a gas along with other oxides of nitrogen. Many epidemiological studies have e...
متن کاملnitrogen dioxide in school children
Objectives-To assess the distribution of personal exposures to nitrogen dioxide (NO2) in school children, and to investigate factors that might influence personal exposure. Methods-NO, exposures were assessed by use of passive diffusion tubes for 46 children aged 9-11 years, selected from two Southampton schools. The tubes were worn for seven days, and parallel measurements were made with stati...
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Results from air pollution exposure assessment studies suggest that ambient fine particles [particulate matter with aerodynamic diameter<or=2.5 microg (PM2.5)], but not ambient gases, are strong proxies of corresponding personal exposures. For particles, the strength of the personal-ambient association can differ by particle component and level of home ventilation. For gases, however, such as o...
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ورودعنوان ژورنال:
- Environmental Health Perspectives
دوره 19 شماره
صفحات -
تاریخ انتشار 1977